A young man has a horrible motorcycle accident. He wakes up in the hospital to discover that one of his arms has been amputated. Then a portrait on the wall of his hospital room begins to speak to him. The subject of the painting introduces himself as Ambroise Paré, the French barber-surgeon who revolutionized the art of amputation. From this wonderfully absurd premise, the two begin an imaginary conversation that takes them through a sweeping history of surgical amputation, from the Stone Age to the Space Age. Unencumbered by pathos or pedagogy, this graphic novel explores the world of amputation, revealing fascinating details about famous amputees throughout history, the invention of the tourniquet, phantom limb syndrome, types of prostheses, and transhumanist technologies.