The Infinity Stones have returned to the Marvel Universe! Who will wield their unbelievable cosmic power this time? The answers unite some of Marvel's biggest names with its newest breakout characters! From iconic figures Iron Man, Captain America, Thor and Spider-Man to fan-favorites Miles Morales and the Black Cat to super-teams the Avengers and the Guardians of the Galaxy, they'll all have their hands full with rising stars including Quantum, Overtime, the White Fox, Taegukgi and more! Meanwhile, Nick Fury undertakes his own quest to track down answers about the Infinity Stones! Collecting IRON MAN ANNUAL (2021) #1, CAPTAIN AMERICA ANNUAL (2021) #1, THOR ANNUAL (2021) #1, BLACK CAT ANNUAL (2021) #1, AVENGERS ANNUAL (2021) #1, MILES MORALES: SPIDER-MAN ANNUAL #1, GUARDIANS OF THE GALAXY ANNUAL (2021) #1 and AMAZING SPIDER-MAN ANNUAL (2018) #2.