Gwen Stacy, the former Spider-Woman of Earth-65, makes her way to the Marvel Universe! With a cloud of infamy hanging over her head in her home dimension, Gwen now travels to the Prime Marvel Universe for super hero action...and school?! The newest student at ESU is about to get a crash course in multiversity as she splits her time between the world she loves and the world she's just getting to know! But what devious villain has their eyes on Gwen's travels? And is Gwen Stacy, the newly minted Ghost-Spider, ready for what comes next?